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	Provedor de dados BJMBR (2) Autor Brosnihan,K.B. (2) Anton,L. (1) Ferrario,C.M. (1) Joyner,J. (1) Li,P. (1) Merrill,D.C. (1) Neves,L.A.A. (1) Senanayake,P.S. (1) Valdes,G. (1) Mais... Palavra-chave Angiotensin converting enzyme (1) Angiotensin peptides (1) Angiotensin receptors (1) Angiotensin-(1-7) (1) Bradykinin (1) Hormone replacement (1) Kinins (1) Nitric oxide (1) Preeclampsia (1) Pregnancy (1) Renin (1) Renin-angiotensin system (1) Vasodilation (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2004 (1) 1999 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Bi-directional actions of estrogen on the renin-angiotensin system BJMBR Brosnihan,K.B.; Senanayake,P.S.; Li,P.; Ferrario,C.M.. Estrogen stimulates the renin-angiotensin system by augmenting both tissue and circulating levels of angiotensinogen and renin. We show, however, that angiotensin converting enzyme (ACE) activity in the circulation and in tissues is reduced in two animal models of postmenopausal chronic hormone replacement. We observed a reduction of ACE activity in association with a significant increase in plasma angiotensin I (Ang I) and hyperreninemia in ovariectomized monkeys treated with Premarin (conjugated equine estrogen) replacement for 30 months. Plasma angiotensin II (Ang II) levels were not increased in monkeys treated with estrogen, suggesting that the decrease in ACE curtailed the formation of the peptide. The Ang II/Ang I ratio, an in vivo index of ACE... Tipo: Info:eu-repo/semantics/article Palavras-chave: Renin; Angiotensin converting enzyme; Angiotensin peptides; Angiotensin receptors; Bradykinin; Nitric oxide; Kinins; Vasodilation; Hormone replacement. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000400001 Enhanced expression of Ang-(1-7) during pregnancy BJMBR Brosnihan,K.B.; Neves,L.A.A.; Anton,L.; Joyner,J.; Valdes,G.; Merrill,D.C.. Pregnancy is a physiological condition characterized by a progressive increase of the different components of the renin-angiotensin system (RAS). The physiological consequences of the stimulated RAS in normal pregnancy are incompletely understood, and even less understood is the question of how this system may be altered and contribute to the hypertensive disorders of pregnancy. Findings from our group have provided novel insights into how the RAS may contribute to the physiological condition of pregnancy by showing that pregnancy increases the expression of both the vasodilator heptapeptide of the RAS, angiotensin-(1-7) [Ang-(1-7)], and of a newly cloned angiotensin converting enzyme (ACE) homolog, ACE2, that shows high catalytic efficiency for Ang II... Tipo: Info:eu-repo/semantics/article Palavras-chave: Pregnancy; Renin-angiotensin system; Preeclampsia; Angiotensin-(1-7). Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000800017 Registros recuperados: 2 Primeira ... 1 ... Última

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